Combination of Ipilimumab and Adoptive Cell Therapy with Tumor-Infiltrating Lymphocytes for Patients with Metastatic Melanoma

PurposeAdoptive cell therapy (ACT) using tumor-infiltrating lymphocytes (TIL) for metastatic melanoma can be highly effective, but attrition due to progression before TIL administration (32% in prior institutional experience) remains a limitation. We hypothesized that combining ACT with cytotoxic T...

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Autori principali:	John E. Mullinax, MacLean Hall, Sangeetha Prabhakaran, Jeffrey Weber, Nikhil Khushalani, Zeynep Eroglu, Andrew S. Brohl, Joseph Markowitz, Erica Royster, Allison Richards, Valerie Stark, Jonathan S. Zager, Linda Kelley, Cheryl Cox, Vernon K. Sondak, James J. Mulé, Shari Pilon-Thomas, Amod A. Sarnaik
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2018-03-01
Serie:	Frontiers in Oncology
Soggetti:	adoptive cell therapy melanoma ipilimumab checkpoint inhibitor immunotherapy tumor-infiltrating lymphocytes
Accesso online:	http://journal.frontiersin.org/article/10.3389/fonc.2018.00044/full
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