Probability fluxes and transition paths in a Markovian model describing complex subunit cooperativity in HCN2 channels.
Hyperpolarization-activated cyclic nucleotide-modulated (HCN) channels are voltage-gated tetrameric cation channels that generate electrical rhythmicity in neurons and cardiomyocytes. Activation can be enhanced by the binding of adenosine-3',5'-cyclic monophosphate (cAMP) to an intracellular cyclic...
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| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science (PLoS)
2012-01-01
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| coleção: | PLoS Computational Biology |
| Acesso em linha: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23093920/pdf/?tool=EBI |
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