Naringin Ameliorates Monocrotaline-Induced Pulmonary Arterial Hypertension Through Endothelial-To-Mesenchymal Transition Inhibition

Pulmonary arterial hypertension (PAH) caused by enhanced arterial pressure increases vessel resistance in the lung. Endothelial-to-mesenchymal transition (EndMT) plays key roles in the vascular remodeling in PAH. Naringin, a protective gaseous mediator is commonly extracted from tomatoes and citrus...

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Hlavní autoři:	Yonghui Wu, Changhong Cai, Yijia Xiang, Huan Zhao, Lingchun Lv, Chunlai Zeng
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2021-07-01
Edice:	Frontiers in Pharmacology
Témata:	naringin pulmonary arterial hypertension endothelial-to-mesenchymal transition monocrotaline endothelial cell rat
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fphar.2021.696135/full
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