Influence of tryptophan contained in 1-Methyl-Tryptophan on antimicrobial and immunoregulatory functions of indoleamine 2,3-dioxygenase.

Indoleamine 2,3-dioxygenase (IDO) has been identified as an important antimicrobial and immunoregulatory effector molecule essential for the establishment of tolerance by regulating local tryptophan (Trp) concentrations. On the other hand, the immunosuppressive capacity of IDO can have detrimental e...

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Detalhes bibliográficos

Principais autores:	Silvia K Schmidt, Stephan Siepmann, Katja Kuhlmann, Helmut E Meyer, Sabine Metzger, Sabine Pudelko, Margret Leineweber, Walter Däubener
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2012-01-01
Colecção:	PLoS ONE
Acesso em linha:	http://europepmc.org/articles/PMC3441469?pdf=render
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