PD-L1 and ICAM1 over expression empowers immunoregulation of mesenchymal stromal cells to improve the autoimmune hepatitis treatment efficacy

Abstract Background Autoimmune hepatitis (AIH) is an immune-mediated disease for which there is no effective treatment. Mesenchymal stromal cells (MSCs) have become a promising treatment, but low AIH treatment efficacy has hampered the clinical application of MSCs. Methods By using Good Manufacturin...

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Autori principali:	Xilong Bai, Tingting Liu, Congge Li, Caie Qiu, Xiaofan Ge, Huili Gou, Hongzhi Cai, Liting Yang, Sili Wei, Wei Yang, Tianqing Li
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2025-04-01
Serie:	Stem Cell Research & Therapy
Soggetti:	Mesenchymal stromal cells PD-L1 ICAM1 Empowered immunoregulation Autoimmune hepatitis
Accesso online:	https://doi.org/10.1186/s13287-025-04347-w
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