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Analysis of the combined effect of rs699 and rs5051 on angiotensinogen expression and hypertension

Abstract Background Hypertension (HTN) involves genetic variability in the renin‐angiotensin system and influences antihypertensive response. We previously reported that angiotensinogen (AGT) messenger RNA (mRNA) is endogenously bound by miR‐122‐5p and rs699 A > G decreases reporter mRNA in the micr...

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Auteurs principaux: Nicholas R. Powell, Tyler Shugg, Jacob Leighty, Matthew Martin, Rolf P. Kreutz, Michael T. Eadon, Dongbing Lai, Tao Lu, Todd C. Skaar
Format: Artigo
Langue:Inglês
Publié: Wiley 2024-06-01
Collection:Chronic Diseases and Translational Medicine
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Accès en ligne:https://doi.org/10.1002/cdt3.103
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