An immortalized adipose-derived stem cells line from the PIK3CA-related overgrowth spectrum: Unveiling novel therapeutic targets

PIK3CA-related overgrowth spectrum (PROS) encompasses several rare conditions that lead to overgrowth of various body parts resulting from activating variants in PIK3CA. The absence of ideal cell models significantly impedes progress in PROS research. In this study, we focused on facial infiltrating...

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Detalhes bibliográficos

Principais autores:	Bin Sun, Hongrui Chen, Wei Gao, Yunqi Li, Chen Hua, Xiaoxi Lin
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-12-01
coleção:	Biochemistry and Biophysics Reports
Assuntos:	PIK3CA-Related overgrowth spectrum Facial infiltrating lipomatosis Immortalization ADSCs Target therapy
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2405580824002334
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