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Sugen kinase 495 promotes the proliferation, migration and invasion of lung squamous cell carcinoma cells by targeting Foxo1 transcription factor

Abstract Sugen kinase 495 (Sgk495), also known as Serine/Threonine Kinase 40 (STK40), is a pseudokinase previously implicated in T cell differentiation via regulation of Foxo transcription factors. However, its function and mechanism in lung squamous cell carcinoma (LUSC) remain unclear. Here, we re...

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主要な著者: Yuanmei Lou, Jun Chen, Yangpeng Tang, Yingying Zhou, Chaowu Liu, Lin Mi, Hanbo Le, Zhijun Chen
フォーマット: Artigo
言語:Inglês
出版事項: BMC 2026-03-01
シリーズ:Cancer Cell International
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オンライン・アクセス:https://doi.org/10.1186/s12935-026-04267-6
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