GWAS and 3D chromatin mapping identifies multicancer risk genes associated with hormone-dependent cancers.

Hormone-dependent cancers (HDCs) share several risk factors, suggesting a common aetiology. Using data from genome-wide association studies, we showed spatial clustering of risk variants across four HDCs (breast, endometrial, ovarian and prostate cancers), contrasting with genetically uncorrelated t...

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Hlavní autoři:	Isela Sarahi Rivera, Juliet D French, Mainá Bitar, Haran Sivakumaran, Sneha Nair, Susanne Kaufmann, Kristine M Hillman, Mahdi Moradi Marjaneh, Jonathan Beesley, Stacey L Edwards
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Public Library of Science (PLoS) 2024-11-01
Edice:	PLoS Genetics
On-line přístup:	https://doi.org/10.1371/journal.pgen.1011490
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