Implantation of biomimetic polydopamine nanocomposite scaffold promotes optic nerve regeneration through modulating inhibitory microenvironment

Abstract Optic nerve regeneration remains challenging worldwide due to the limited intrinsic regenerative capacity of retinal ganglion cells (RGCs) and the inhibitory microenvironment. Oxidative stress, induced by excessive reactive oxygen species (ROS) following optic nerve injury, is associated wi...

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Principais autores:	Tonghe Pan, Yate Huang, Jinfei Wei, Chen Lai, Yangjun Chen, Kaihui Nan, Wencan Wu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2024-11-01
coleção:	Journal of Nanobiotechnology
Assuntos:	Biomimetic scaffold Reactive oxygen species Polydopamine nanoparticles Microenvironment modulation Optic nerve regeneration
Acesso em linha:	https://doi.org/10.1186/s12951-024-02962-y
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