Live imaging and tracking of genome regions in CRISPR/dCas9 knock-in mice
Abstract CRISPR/dCas9 is a versatile tool that can be used to recruit various effectors and fluorescent molecules to defined genome regions where it can modulate genetic and epigenetic markers, or track the chromatin dynamics in live cells. In vivo applications of CRISPR/dCas9 in animals have been c...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BMC
2018-11-01
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| Edice: | Genome Biology |
| Témata: | |
| On-line přístup: | http://link.springer.com/article/10.1186/s13059-018-1530-1 |
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