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ASPM-associated stem cell proliferation is involved in malignant progression of gliomas and constitutes an attractive therapeutic target

<p>Abstract</p> <p>Background</p> <p>ASPM (<it>Abnormal Spindle-like Microcephaly associated</it>) over-expression was recently implicated in the development of malignant gliomas.</p> <p>Results</p> <p>To better characterize the involvement of ASPM in gliomas, we investigated the mRNA expression in...

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Autores principales: Calvo Charles, Boisselier Blandine, Idbaih Ahmed, Rousseau Audrey, Ravassard Philippe, Vampouille Raphaël, Marie Yannick, Colin Carole, Bikeye Sandra-Nadia, Leuraud Pascal, Lassalle Myriam, El Hallani Soufiane, Delattre Jean-Yves, Sanson Marc
Formato: Artigo
Lenguaje:Inglês
Publicado: BMC 2010-01-01
Colección:Cancer Cell International
Acceso en línea:http://www.cancerci.com/content/10/1/1
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