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Wip1 and p53 contribute to HTLV-1 Tax-induced tumorigenesis

<p>Abstract</p> <p>Background</p> <p>Human T-cell Leukemia Virus type 1 (HTLV-1) infects 20 million individuals world-wide and causes Adult T-cell Leukemia/Lymphoma (ATLL), a highly aggressive T-cell cancer. ATLL is refractory to treatment with conventional chemotherapy and fewer than 10% of afflict...

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Auteurs principaux: Zane Linda, Yasunaga Junichiro, Mitagami Yu, Yedavalli Venkat, Tang Sai-Wen, Chen Chia-Yen, Ratner Lee, Lu Xiongbin, Jeang Kuan-Teh
Format: Artigo
Langue:Inglês
Publié: BMC 2012-12-01
Collection:Retrovirology
Accès en ligne:http://www.retrovirology.com/content/9/1/114
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