Gain of function in Mycobacterium bovis BCG Moreau due to loss of a transcriptional repressor
The Bacille Calmette-Guérin (BCG) vaccine comprises a family of genetically different strains derived by the loss of genomic regions (RDs) and other mutations. In BCG Moreau, loss of RD16 inactivates rv3405c * , encoding a transcriptional repressor that negatively regulates the expression of Rv3406...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
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Fundação Oswaldo Cruz (FIOCRUZ)
2018-10-01
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| Schriftenreihe: | Memorias do Instituto Oswaldo Cruz |
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| Online-Zugang: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762018001100400&lng=en&tlng=en |
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