HIV-1 infection of macrophages differentially primes NK-cell cytotoxicity and proinflammatory cytokine production

Summary: Natural killer (NK) cells are innate cytotoxic lymphocytes with antiviral functions explored in “shock and kill” strategies to eliminate the HIV-1 reservoir. For optimal activity against infected targets, NK cells require priming. This study examined how macrophages prime NK cells following...

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मुख्य लेखकों:	Leonore Mensching, Maya Beiersdorfer, Sebastian Schloer, Sandra Köllmann, Friederike Reinsberg, Benedetta Padoan, Pia Fittje, Timo Trenkner, Annika Zaayenga, Gloria Martrus, Maher Almahfoud, Christina M. Stürzel, Daniel Sauter, Frank Kirchhoff, Julian Schulze zur Wiesch, Marcus Altfeld, Wilfredo F. Garcia-Beltran, Angelique Hoelzemer
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	Elsevier 2025-07-01
श्रृंखला:	iScience
विषय:	Immunology Immune response Virology
ऑनलाइन पहुंच:	http://www.sciencedirect.com/science/article/pii/S258900422501140X
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