Synergistic anti-proliferative activity of JQ1 and GSK2801 in triple-negative breast cancer

Abstract Background Triple-negative breast cancer (TNBC) constitutes 10–20% of breast cancers and is challenging to treat due to a lack of effective targeted therapies. Previous studies in TNBC cell lines showed in vitro growth inhibition when JQ1 or GSK2801 were administered alone, and enhanced act...

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Detalhes bibliográficos

Principais autores:	Nanda Kumar Yellapu, Thuc Ly, Mihaela E. Sardiu, Dong Pei, Danny R. Welch, Jeffery A. Thompson, Devin C. Koestler
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2022-06-01
coleção:	BMC Cancer
Assuntos:	Breast cancer RNASeq Differential expression analysis Drug resistance Expression studies MTT assay
Acesso em linha:	https://doi.org/10.1186/s12885-022-09690-2
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