Development of different degrees of elastase-induced emphysema in mice: a randomized controlled experimental studyenfisema pulmonar, mecânica pulmonar, elastase pancreática.

Introduction: Mouse models of emphysema are important tools for testing different therapeutic strategies. The aim of this study was to develop a mouse model of emphysema induced by different doses of elastase in order to produce different degrees of severity. Methods: Thirty female mice (C57BL/6) w...

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Principais autores:	Cristiana Palma Kuhl, Tuane Nerissa Alves Garcez, Alessandra Bileski Magrisso, Claudia Cilene Fernandes Correia Laurino, Elizabeth Obino Cirne-Lima, Patricia Rieken Macedo Rocco, Amarilio Vieira de Macedo Neto
Formato:	Artigo
Idioma:	Inglês
Publicado:	Hospital de Clinicas de Porto Alegre ; Universidade Federal do Rio Grande do Sul (UFRGS) 2014-10-01
Series:	Clinical and Biomedical Research
Assuntos:	Pulmonary emphysema Lung mechanics Pancreatic elastase.
Acceso en liña:	http://seer.ufrgs.br/hcpa/article/view/48676
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