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Peptide nano-blanket impedes fibroblasts activation and subsequent formation of pre-metastatic niche

Primary tumors “spread the spark” by establishing a pre-metastatic niche. Here the authors develop an in-situ assembled peptide FR17 to serve as a “flame-retarding blanket” to extinguish the “fire” of the pre-metastatic microenvironment.

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Auteurs principaux: Yi Zhou, Peng Ke, Xiaoyan Bao, Honghui Wu, Yiyi Xia, Zhentao Zhang, Haiqing Zhong, Qi Dai, Linjie Wu, Tiantian Wang, Mengting Lin, Yaosheng Li, Xinchi Jiang, Qiyao Yang, Yiying Lu, Xincheng Zhong, Min Han, Jianqing Gao
Format: Artigo
Langue:Inglês
Publié: Nature Portfolio 2022-05-01
Collection:Nature Communications
Accès en ligne:https://doi.org/10.1038/s41467-022-30634-8
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