Yeast-two-hybrid based high-throughput screening to discover SARS-CoV-2 fusion inhibitors by targeting the HR1/HR2 interaction

The continuous emergence of SARS-CoV-2 variants as well as other potential future coronavirus has challenged the effectiveness of current COVID-19 vaccines. Therefore, there remains a need for alternative antivirals that target processes less susceptible to mutations, such as the formation of six-he...

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Главные авторы:	Jing Zhang, Dongsheng Li, Wenwen Zhou, Chao Liu, Peirong Wang, Baoqing You, Bingjie Su, Keyu Guo, Wenjing Shi, Tin Mong Timothy Yung, Richard Yi Tsun Kao, Peng Gao, Yan Li, Shuyi Si
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Elsevier 2025-09-01
Серии:	Acta Pharmaceutica Sinica B
Предметы:	SARS-CoV-2 HR1/HR2 interaction Yeast-two-hybrid High-throughput screening IMB-9C Fusion inhibitor
Online-ссылка:	http://www.sciencedirect.com/science/article/pii/S221138352500454X
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