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Novel potential pharmacological applications of dimethyl fumarate—an overview and update

Dimethyl fumarate (DMF) is an FDA-approved drug for the treatment of psoriasis and multiple sclerosis. DMF is known to stabilize the transcription factor Nrf2, which in turn induces the expression of antioxidant response element genes. It has also been shown that DMF influences autophagy and partici...

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Autors principals: Giorgia Bresciani, Federico Manai, Sergio Davinelli, Paolo Tucci, Luciano Saso, Marialaura Amadio
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2023-09-01
Col·lecció:Frontiers in Pharmacology
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Accés en línia:https://www.frontiersin.org/articles/10.3389/fphar.2023.1264842/full
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