Integrative miRNA-mRNA profiling uncovers mechanisms of belimumab action in systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is a complex autoimmune disorder driven by autoreactive B cells and characterized by the production of pathogenic autoantibodies. Belimumab, an anti-BAFF monoclonal antibody, has demonstrated efficacy in reducing disease activity and corticosteroid use in SLE patie...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Maria Royo, Blanca Joseph-Mullol, Sebastian Sandoval, Teresa Moliné, Cristina Solé, Josefina Cortés-Hernández
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2025-03-01
Schriftenreihe:	Frontiers in Immunology
Schlagworte:	systemic lupus erythematosus miRNA mRNA integrative “omics” belimumab mechanism of action
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1553971/full
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!