Experimentally derived biomimetic chromatographic descriptors for drug-induced phospholipidosis liability prediction
Background and purpose: Drug-induced phospholipidosis (PLD) is a complex intracellular liability commonly associated with the lysosomal accumulation of cationic amphiphilic drugs and remains an important concern in drug development because of its implications for safety, intracellular disposition,...
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| Principais autores: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International Association of Physical Chemists (IAPC)
2026-07-01
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| coleção: | ADMET and DMPK |
| Assuntos: | |
| Acesso em linha: | https://pub.iapchem.org/ojs/index.php/admet/article/view/3460 |
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