Quantitative plasma proteomics identifies metallothioneins as a marker of acute-on-chronic liver failure associated acute kidney injury

BackgroundAcute kidney injury (AKI) considerably increases the risk of short-term mortality in acute-on-chronic liver failure (ACLF) but predicting AKI is not possible with existing tools. Our study aimed at de novo discovery of AKI biomarkers in ACLF.MethodsThis observational study had two phases-...

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Autori principali:	Pragyan Acharya, Rohini Saha, Javed Ahsan Quadri, Saba Sarwar, Maroof Ahmad Khan, Hem Chandra Sati, Nidhi Gauniyal, Ahmadullah Shariff, Shekhar Swaroop, Piyush Pathak, Shalimar
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2023-01-01
Serie:	Frontiers in Immunology
Soggetti:	ACLF AKI proteomics biomarkers metallothionein inflammation
Accesso online:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.1041230/full
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