Macrophage inhibitory cytokine-1 (MIC-1/GDF15) slows cancer development but increases metastases in TRAMP prostate cancer prone mice.

Macrophage inhibitory cytokine-1 (MIC-1/GDF15), a divergent member of the TGF-β superfamily, is over-expressed by many common cancers including those of the prostate (PCa) and its expression is linked to cancer outcome. We have evaluated the effect of MIC-1/GDF15 overexpression on PCa development an...

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Главные авторы:	Yasmin Husaini, Min Ru Qiu, Glen P Lockwood, Xu Wei Luo, Ping Shang, Tamara Kuffner, Vicky Wang-Wei Tsai, Lele Jiang, Pamela J Russell, David A Brown, Samuel N Breit
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Public Library of Science (PLoS) 2012-01-01
Серии:	PLoS ONE
Online-ссылка:	http://europepmc.org/articles/PMC3428289?pdf=render
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