Remimazolam-induced anesthesia does not affect circadian rhythms significantly in mice

Abstract Although inhalational general anesthesia affects mammalian circadian rhythms, which are generated through oscillations in expression of clock genes in the suprachiasmatic nucleus (SCN), the impact of intravenous benzodiazepine (BDZ)-induced general anesthesia is not well understood. We inve...

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Hlavní autoři:	Yasuhito Suzuki, Ryo Imai, Yoshitaka Aoki, Shingo Kawashima, Kazuya Hokamura, Tetsuro Kimura, Tadayoshi Kurita, Takasumi Katoh, Soichiro Mimuro, Hiroshi Makino, Kazuo Umemura, Yoshiki Nakajima
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2025-11-01
Edice:	Scientific Reports
Témata:	Circadian rhythm Remimazolam Benzodiazepine Perioperative complications
On-line přístup:	https://doi.org/10.1038/s41598-025-29999-9
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