Assessing the function of pneumococcal neuraminidases NanA, NanB and NanC in in vitro and in vivo lung infection models using monoclonal antibodies

Streptococcus pneumoniae isolates express up to three neuraminidases (sialidases), NanA, NanB and NanC, all of which cleave the terminal sialic acid of glycan-structures that decorate host cell surfaces. Most research has focused on the role of NanA with limited investigations evaluating the roles o...

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Autors principals:	Philipp Janesch, Harald Rouha, Adriana Badarau, Lukas Stulik, Irina Mirkina, Marisa Caccamo, Katharina Havlicek, Barbara Maierhofer, Susanne Weber, Karin Groß, Jacqueline Steinhäuser, Manuel Zerbs, Cecilia Varga, Ivana Dolezilkova, Sabine Maier, Gerhild Zauner, Nels Nielson, Christine A. Power, Eszter Nagy
Format:	Artigo
Idioma:	Inglês
Publicat:	Taylor & Francis Group 2018-12-01
Col·lecció:	Virulence
Matèries:	Streptococcus pneumoniae neuraminidases NanA NanB NanC human and mouse lung infection models host-pathogen interactions monoclonal antibodies
Accés en línia:	http://dx.doi.org/10.1080/21505594.2018.1520545
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