Structure of the IL-27 quaternary receptor signaling complex
Interleukin 27 (IL-27) is a heterodimeric cytokine that functions to constrain T cell-mediated inflammation and plays an important role in immune homeostasis. Binding of IL-27 to cell surface receptors, IL-27Rα and gp130, results in activation of receptor-associated Janus Kinases and nuclear translo...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
eLife Sciences Publications Ltd
2022-05-01
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| Σειρά: | eLife |
| Θέματα: | |
| Διαθέσιμο Online: | https://elifesciences.org/articles/78463 |
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