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HURP regulates Kif18A recruitment and activity to synergistically control microtubule dynamics

Abstract During mitosis, microtubule dynamics are regulated to ensure proper alignment and segregation of chromosomes. The dynamics of kinetochore-attached microtubules are regulated by hepatoma-upregulated protein (HURP) and the mitotic kinesin-8 Kif18A, but the underlying mechanism remains elusive...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Juan M. Perez-Bertoldi, Yuanchang Zhao, Akanksha Thawani, Ahmet Yildiz, Eva Nogales
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Portfolio 2024-11-01
Cyfres:Nature Communications
Mynediad Ar-lein:https://doi.org/10.1038/s41467-024-53691-7
Tagiau: Ychwanegu Tag
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