Donor-derived cell-free DNA detects kidney transplant rejection during nivolumab treatment

Abstract Background In solid organ transplant (SOT) recipients, transplant rejection during immune checkpoint inhibitor (ICI) treatment for cancer is a clinical problem. Donor-derived cell-free DNA (dd-cfDNA) can be detected in blood and is a sensitive biomarker for diagnosis of acute rejection in S...

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Principais autores:	Daan P. Hurkmans, Jeroen G. H. P. Verhoeven, Kitty de Leur, Karin Boer, Arjen Joosse, Carla C. Baan, Jan H. von der Thüsen, Ron H. N. van Schaik, Ron H. J. Mathijssen, Astrid A. M. van der Veldt, Dennis A. Hesselink
Format:	Artigo
Jezik:	Inglês
Izdano:	BMJ Publishing Group 2019-07-01
Serija:	Journal for ImmunoTherapy of Cancer
Teme:	Allograft rejection Anti-PD-1 Dd-cfDNA Melanoma Donor-derived cell-free DNA Immune checkpoint inhibition
Online dostop:	http://link.springer.com/article/10.1186/s40425-019-0653-6
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