Fundamental properties of the mammalian innate immune system revealed by multispecies comparison of type I interferon responses.
The host innate immune response mediated by type I interferon (IFN) and the resulting up-regulation of hundreds of interferon-stimulated genes (ISGs) provide an immediate barrier to virus infection. Studies of the type I 'interferome' have mainly been carried out at a single species level, often lac...
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| Principais autores: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science (PLoS)
2017-12-01
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| coleção: | PLoS Biology |
| Acesso em linha: | https://doi.org/10.1371/journal.pbio.2004086 |
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