Memory T cells: A helpful guard for allogeneic hematopoietic stem cell transplantation without causing graft-versus-host disease

Graft-versus-host disease (GVHD) is a major complication of allogeneic hematopoietic stem cell transplantation (AHSCT) and the major cause of nonrelapse morbidity and mortality of AHSCT. In AHSCT, donor T cells facilitate hematopoietic stem cell (HSC) engraftment, contribute to anti-infection immuni...

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Bibliografische Detailangaben

Hauptverfasser:	Wei Huang, Nelson J. Chao
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Wolters Kluwer Medknow Publications 2017-10-01
Schriftenreihe:	Hematology/Oncology and Stem Cell Therapy
Schlagworte:	graft-versus-host disease graft-versus-leukemia hematopoietic stem cell transplantation memory t cells t-cell exhaustion t-cell metabolism
Online-Zugang:	https://journals.lww.com/10.1016/j.hemonc.2017.05.006
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