Diversities of African swine fever virus host-virus dynamics revealed by single-cell profiling

ABSTRACT African swine fever virus (ASFV) causes epidemics with high mortality; however, effective vaccines and therapies remain missing. Here, we depict a temporal single-cell landscape of primary porcine alveolar macrophages (PAMs) exposed to three different virulent ASFV strains in vitro. We foun...

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Bibliographic Details
Main Authors: Xiaoyang Zhao, Yanyan Zhang, Hanying Jia, Lin Lv, Md.Asif Ahsan, Xudong Fu, Rongliang Hu, Zhiqiang Shen, Ning Shen
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2025-03-01
Series:Journal of Virology
Subjects:
single-cell RNA sequencing
African swine fever virus
host-virus interaction
macrophage
Online Access:https://journals.asm.org/doi/10.1128/jvi.02035-24
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