A cell-impermeable kinase inhibitor uncovers outside-in signaling pathways that promote HIV-1 infection

ABSTRACT Studies of herpes simplex virus (HSV) entry revealed a previously unrecognized “outside-in” signaling pathway involving phosphatidylserine (PS) scrambling and associated translocation and subsequent extracellular activation of canonical intracellular proteins, including Akt. We hypothesized...

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Үндсэн зохиолчид:	Kelsey Vinzant, Natalia Cheshenko, Heng Pan, Ronald Cutler, Joshua N. Buckler, Andreas Luxenburger, Lawrence D. Harris, Jeffrey R. Johnson, Steven C. Almo, Betsy C. Herold
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	American Society for Microbiology 2026-06-01
Цуврал:	Journal of Virology
Нөхцлүүд:	TMEM16F glypican-1 T cells kinase inhibitor HIV-1
Онлайн хандалт:	https://journals.asm.org/doi/10.1128/jvi.00160-26
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!