Cold Spot SCANNER: Colab Notebook for predicting cold spots in protein–protein interfaces

Abstract Background Protein–protein interactions (PPIs) are conveyed through binding interfaces or surface patches on proteins that become buried upon binding. Structural and biophysical analysis of many protein–protein interfaces revealed certain unique features of these surfaces that determine the...

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Principais autores:	Sagara N. S. Gurusinghe, Julia M. Shifman
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2024-04-01
coleção:	BMC Bioinformatics
Assuntos:	Protein–protein interactions Cold spots Cavities Binding interface Binding affinity
Acesso em linha:	https://doi.org/10.1186/s12859-024-05796-5
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