Significance of Matrix Metalloproteinase-9 Inhibition by Imidapril for Prevention of Abdominal Aortic Aneurysms in Angiotensin II Type 1 Receptor–Knockout Mice

To clarify the matrix metalloproteinase (MMP)-9 inhibitory effect of an angiotensin-converting enzyme (ACE) inhibitor in vivo, we evaluated the effect of an ACE inhibitor against elastase-induced abdominal aortic aneurysm (AAA) progression in mice. Molecular models showed that imidapril bound direct...

Cijeli opis

Bibliografski detalji

Glavni autori:	Shinji Takai, Denan Jin, Daisuke Yamamoto, Zhong-Lian Li, Yoshinori Otsuki, Mizuo Miyazaki
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2013-01-01
Serija:	Journal of Pharmacological Sciences
Online pristup:	http://www.sciencedirect.com/science/article/pii/S1347861319302695
Oznake:	Dodaj oznaku Bez oznaka, Budi prvi tko označuje ovaj zapis!