Cholinergic Interneurons Amplify Corticostriatal Synaptic Responses in the Q175 Model of Huntington’s Disease

Huntington’s disease (HD) is a neurodegenerative disorder characterized by deficits in movement control that are widely viewed as stemming from pathophysiological changes in the striatum. Giant, aspiny cholinergic interneurons (ChIs) are key elements in the striatal circuitry controlling movement, b...

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Bibliografske podrobnosti

Principais autores:	Asami Tanimura, Sean Austin Ong Lim, Jose de Jesus Aceves Buendia, Joshua A Goldberg, Dalton J Surmeier
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2016-12-01
Serija:	Frontiers in Systems Neuroscience
Teme:	Ranolazine channelrhodopsin-2 EPSC persistent Na+ current Paired-pulse ratio glutamatergic transmission
Online dostop:	http://journal.frontiersin.org/Journal/10.3389/fnsys.2016.00102/full
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