Pre-vaccination inflammation and B-cell signalling predict age-related hyporesponse to hepatitis B vaccination
Ageing is associated with poor responses to vaccines but the underlying mechanism remains unclear. Here the authors use a systems-based approach to define molecular signatures present before vaccination that correlate with non-responsiveness to hepatitis B vaccination in healthy, elderly adults.
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| Principais autores: | , , , , , , , , , , , , , , |
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| 格式: | Artigo |
| 语言: | Inglês |
| 出版: |
Nature Portfolio
2016-01-01
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| 丛编: | Nature Communications |
| 在线阅读: | https://doi.org/10.1038/ncomms10369 |
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