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DNA repair genes in astrocytoma tumorigenesis, progression and therapy resistance

Abstract Glioblastoma (GBM) is the most common and malignant type of primary brain tumor, showing rapid development and resistance to therapies. On average, patients survive 14.6 months after diagnosis and less than 5% survive five years or more. Several pieces of evidence have suggested that the DN...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Juliana Ferreira de Sousa, Rodolfo Bortolozo Serafim, Laura Marise de Freitas, Carla Raquel Fontana, Valeria Valente
Format: Artigo
Sprache:Inglês
Veröffentlicht: Sociedade Brasileira de Genética 2019-12-01
Schriftenreihe:Genetics and Molecular Biology
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Online-Zugang:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572020000200306&tlng=en
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