Syk activation during FcγR-mediated phagocytosis involves Syk palmitoylation and desulfenylation
Upon Fc gamma R–mediated phagocytosis, Syk is palmitoylated by DHHC5 and desulfenylated on nearby Cys residues, and both modifications are important for Syk phosphorylation and phagocytosis. The Syk tyrosine kinase acts downstream of several immune receptors such as the FcγR. Syk owns two SH2 domain...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Life Science Alliance LLC
2026-04-01
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| Edice: | Life Science Alliance |
| On-line přístup: | https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202503500 |
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