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Pneumococcal conjugate vaccines and antimicrobial resistance: serotype replacement, clonal dynamics, and future vaccine perspectives

Pneumococcal conjugate vaccines (PCVs) have transformed the epidemiology of pneumococcal disease while providing a real-world model for understanding how vaccination reshapes antimicrobial resistance (AMR) in Streptococcus pneumoniae. In this Mini Review, we examine PCV-associated AMR dynamics throu...

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Principais autores: Ziyi Yan, Yingying Li, Li Liu, Yanying Ren, Wenjing Wu, Liting Liang, Xingxin Liu, Wei Zhou, Linghan Kuang, Yali Cui, Yongmei Jiang
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2026-07-01
Serier:Frontiers in Immunology
Fag:
antimicrobial resistance
clonal dynamics
global pneumococcal sequence cluster
pneumococcal conjugate vaccine
serotype replacement
Streptococcus pneumoniae
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1903459/full
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