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In Silico Screening and Testing of FDA-Approved Small Molecules to Block SARS-CoV-2 Entry to the Host Cell by Inhibiting Spike Protein Cleavage

The COVID-19 pandemic began in 2019, but it is still active. The development of an effective vaccine reduced the number of deaths; however, a treatment is still needed. Here, we aimed to inhibit viral entry to the host cell by inhibiting spike (S) protein cleavage by several proteases. We developed...

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Hlavní autoři: E. Sila Ozdemir, Hillary H. Le, Adem Yildirim, Srivathsan V. Ranganathan
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2022-05-01
Edice:Viruses
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On-line přístup:https://www.mdpi.com/1999-4915/14/6/1129
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