Meta-Analyses of Splicing and Expression Quantitative Trait Loci Identified Susceptibility Genes of Glioma

BackgroundThe functions of most glioma risk alleles are unknown. Very few studies had evaluated expression quantitative trait loci (eQTL), and insights of susceptibility genes were limited due to scarcity of available brain tissues. Moreover, no prior study had examined the effect of glioma risk all...

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Autors principals:	C. Pawan K. Patro, Darryl Nousome, The Glioma International Case Control Study (GICC), Rose K. Lai, Elizabeth B. Claus, Dora Il’yasova, Joellen Schildkraut, Jill S. Barnholtz-Sloan, Sara H. Olson, Jonine L. Bernstein, Christoffer Johansen, Robert B. Jenkins, Beatrice S. Melin, Margaret R. Wrensch, Richard S. Houlston, Melissa L. Bondy
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2021-04-01
Col·lecció:	Frontiers in Genetics
Matèries:	glioma quantitative trait loci eQTL SQTL summary data based mendelian randomization analyses GWAS
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fgene.2021.609657/full
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