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Mining the transcriptome for rare disease therapies: a comparison of the efficiencies of two data mining approaches and a targeted cell-based drug screen

Rare diseases: drug re-discovery Canadian researchers use three different approaches to identify drugs that could be repurposed to treat rare genetic diseases. Prompted by the growing gap between known rare diseases and therapies and postulating that diseases might be treated with drugs that modulat...

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Principais autores: A. J. Mears, S. C. Schock, J. Hadwen, S. Putos, D. Dyment, K. M. Boycott, Alex MacKenzie
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2017-04-01
coleção:npj Genomic Medicine
Acesso em linha:https://doi.org/10.1038/s41525-017-0018-3
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