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In silico studies and anticancer evaluation of thiazole–pyrazine–thiadiazole amide derivatives: Synthesis, cytotoxic screening, and molecular insights

A new series of thiazole–pyrazine–thiadiazole-based amide derivatives (13a–13j) were designed, synthesized and evaluated for their anticancer activityagainst breast (MCF-7), lung (A549), colon (Colo-205), and ovarian (A2780) cell lines by using the MTT assay method with etoposide as a standard drug,...

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Wedi'i Gadw mewn:
Prif Awduron: Swapna Maarepalli, Savita Belwal, P. Muralidhar Reddy, Suman, Sailam Sri Gogula
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2025-11-01
Cyfres:Results in Chemistry
Pynciau:
Thiazole
Pyrazine
Thiadiazole
Amide derivatives
Anticancer activity
Molecular docking
Mynediad Ar-lein:http://www.sciencedirect.com/science/article/pii/S2211715625007842
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