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Mapping of Recognition Sites of Monoclonal Antibodies Responsible for the Inhibition of Pneumolysin Functional Activity

The pathogenicity of many bacteria, including <i>Streptococcus pneumoniae</i>, depends on pore-forming toxins (PFTs) that cause host cell lysis by forming large pores in cholesterol-containing cell membranes. Therefore, PFTs-neutralising antibodies may provide useful tools for reducing <i>S. pneumon...

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Bibliografische Detailangaben
Hauptverfasser: Indre Kucinskaite-Kodze, Martynas Simanavicius, Justas Dapkunas, Milda Pleckaityte, Aurelija Zvirbliene
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2020-07-01
Schriftenreihe:Biomolecules
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Online-Zugang:https://www.mdpi.com/2218-273X/10/7/1009
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