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A Potent Postentry Restriction to Primate Lentiviruses in a Yinpterochiropteran Bat

ABSTRACT Bats are primary reservoirs for multiple lethal human viruses, such as Ebola, Nipah, Hendra, rabies, severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome-related coronavirus (MERS-CoV), and, most recently, SARS-CoV-2. The innate immune systems of these...

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Main Authors: James H. Morrison, Caitlin Miller, Laura Bankers, Gary Crameri, Lin-Fa Wang, Eric M. Poeschla
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2020-10-01
Series:mBio
Subjects:
retrovirus
HIV-1
lentivirus
bats
restriction factors
cyclophilin A
Online Access:https://journals.asm.org/doi/10.1128/mBio.01854-20
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