Orthosteric and allosteric modulation of human HCAR2 signaling complex

Abstract Hydroxycarboxylic acids are crucial metabolic intermediates involved in various physiological and pathological processes, some of which are recognized by specific hydroxycarboxylic acid receptors (HCARs). HCAR2 is one such receptor, activated by endogenous β-hydroxybutyrate (3-HB) and butyr...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Chunyou Mao, Mengru Gao, Shao-Kun Zang, Yanqing Zhu, Dan-Dan Shen, Li-Nan Chen, Liu Yang, Zhiwei Wang, Huibing Zhang, Wei-Wei Wang, Qingya Shen, Yanhui Lu, Xin Ma, Yan Zhang
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Nature Portfolio 2023-11-01
Цуврал:	Nature Communications
Онлайн хандалт:	https://doi.org/10.1038/s41467-023-43537-z
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!