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Fibroblast bioenergetics to classify amyotrophic lateral sclerosis patients

Abstract Background The objective of this study was to investigate cellular bioenergetics in primary skin fibroblasts derived from patients with amyotrophic lateral sclerosis (ALS) and to determine if they can be used as classifiers for patient stratification. Methods We assembled a collection of un...

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Principais autores: Csaba Konrad, Hibiki Kawamata, Kirsten G. Bredvik, Andrea J. Arreguin, Steven A. Cajamarca, Jonathan C. Hupf, John M. Ravits, Timothy M. Miller, Nicholas J. Maragakis, Chadwick M. Hales, Jonathan D. Glass, Steven Gross, Hiroshi Mitsumoto, Giovanni Manfredi
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2017-10-01
Series:Molecular Neurodegeneration
Assuntos:
Bioenergetics
Mitochondria
ALS
Fibroblasts
PLS
Machine learning
Acceso en liña:http://link.springer.com/article/10.1186/s13024-017-0217-5
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