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No genetic causal association between iron status and osteoporosis: A two-sample Mendelian randomization

ObjectiveTo explore the genetic causal association between osteoporosis (OP) and iron status through Mendelian randomization (MR).MethodsPublicly available genome-wide association study (GWAS) summary data were used for MR analysis with four iron status-related indicators (ferritin, iron, total iron...

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Автори: Jiawen Xu, Jun Ma, Jialei Chen, Shaoyun Zhang, Che Zheng, Haibo Si, Yuangang Wu, Yuan Liu, Mingyang Li, Limin Wu, Bin Shen
Формат: Artigo
Мова:Inglês
Опубліковано: Frontiers Media S.A. 2022-12-01
Серія:Frontiers in Endocrinology
Предмети:
osteoporosis
iron status
causal association
mendelian randomization
genetics
Онлайн доступ:https://www.frontiersin.org/articles/10.3389/fendo.2022.996244/full
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