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Sequence variants in the melatonin-related receptor gene (GPR50) associate with circulating triglyceride and HDL levels

The gene encoding the melatonin-related receptor (GPR50) is highly expressed within hypothalamic nuclei concerned with the control of body weight and metabolism. We screened GPR50 for mutations in an obese cohort and identified an insertion of four amino acid residues (TTGH) at position 501, two com...

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Principais autores: Sumit Bhattacharyya, Jian'an Luan, Benjamin Challis, Julia Keogh, Carl Montague, John Brennand, John Morten, Sarah Lowenbeim, Suzanne Jenkins, I. Sadaf Farooqi, Nicholas J. Wareham, Stephen O'Rahilly
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2006-04-01
Serier:Journal of Lipid Research
Fag:
bipolar
metabolic
neuronal
Online adgang:http://www.sciencedirect.com/science/article/pii/S0022227520332727
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